You can configure Two Factor Authentication on your Signagelive account, provided you are not a Federated user (a user who logs on with SSO).
Users who log in using single-sign-on (i.e., Active Directory, Okta, One Login) will never be challenged for a 2FA code, as their log-in process is managed from the SSO service. Therefore, if you use SSO to log in, the 2FA configuration section will not display in your profile, and the Requires 2FA attribute won’t be available.